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dicer

Dicer is an endoribonuclease in the RNase III family that cleaves double-stranded RNA (dsRNA) and pre-microRNA (miRNA) into short double-stranded RNA fragments called small interfering RNA (siRNA) about 20-25 nucleotides long.

Dicer contains two RNase III domains and one PAZ domain. Dicers interact with several partner proteins. These partner proteins could play a role in dictating the substrate specificity of Dicer proteins.

Dicer facilitates the formation of the RNA-induced silencing complex (RISC), whose catalytic component argonaute is an endonuclease capable of degrading messenger RNA (mRNA). The human version of this gene is DICER1.





Dicer.


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CEBIO

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  • BC AV CR
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  • CZBA
  • Eco Tend
  • Envisan Gem
  • Gentrend
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  • Jihočeská univerzita
  • Madeta
  • Forestina
  • ALIDEA

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