A Shot to Stop Diabetes in Mice - Intervention in Immune Regulation Can Prevent Onset of Type-1 Diabetes
Date: 5.1.2006
Some forms of diabetes could feasibly be prevented. Scientists at the German Research Centre for Biotechnology (GBF) in Braunschweig recently were able to do just that in experiments with mice. Animals with a congenital susceptibility for Type-1 diabetes remained healthy when researchers treated them with an immune regulator shortly after birth.
The substance used prevented the immune systems in mice from mistakenly attacking one of their own molecules found in the pancreas of the animals.
The work group leader, Prof. Jan Buer, stresses that the findings as yet cannot be directly transferred to humans because the molecule studied in the mice strains is not the same one that triggers diabetes in people. However, Dr. Buer is confident that the process could at some point be used as the basis for a diabetes prophylaxis in humans. "It is possible that the same principle might be able to prevent other autoimmune ailments," says Buer.
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