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DNA microscope creates 3D images of organisms from the inside out

28.3.2025: Standard genetic sequencing approaches can tell you a lot about the genetic makeup and activity in a sample, like a piece of tissue or drop of blood. But they don't tell you where specific genetic sequences were located inside that sample, or their relationship to other genes and molecules. Researchers at the University of Chicago are developing a new technology that overcomes these challenges. By tagging each DNA or RNA molecule and allowing neighboring tags to interact, the technique constructs a molecular network that encodes their...

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