At the dawn of the era of genetically engineered crops, scientists were envisioning all sorts of healthier and tastier foods, including cancer-fighting tomatoes, rot-resistant fruits, potatoes that would produce healthier French fries and even beans that would not cause flatulence.
But, so far, most of the genetically modified crops have provided benefits mainly to farmers, by making it easier for them to control weeds and insects.
Now, millions of dollars later, the next generation of crops modified by biotechnology - the first with direct benefits for consumers - is finally on the horizon. But the list does not include many of the products once envisioned.
Developing such crops has proved to be far from easy. Resistance to genetically modified foods, technical difficulties, legal and business obstacles and the ability to develop improved foods without genetic engineering have winnowed the pipeline.
"A lot of companies went into shell shock, I would say, in the past three, four years," said C.S. Prakash, director of plant biotechnology research at Tuskegee University in Alabama. "Because of so much opposition, they've had to put a lot of projects on the shelf."
Developing nonallergenic products and other healthful crops has also proved to be difficult technically. "Changing the food composition is going to be far trickier than just introducing one gene to provide insect resistance," said Prakash, who has promoted agricultural biotechnology on behalf of the industry and the U.S. government.
In 2002, Eliot Herman and his colleagues got some attention when they engineered a soybean to make it less likely to cause an allergic reaction. But the soybean project was put aside because baby-food companies, which he thought would want the soybeans for infant formula, are instead avoiding modified crops, said Herman, a scientist with the Department of Agriculture.
In addition, he said, food companies feared lawsuits if some consumers developed allergic reactions to a product labeled as nonallergenic.
The next generation of these crops - particularly those that provide healthier or tastier food - could be important to consumer acceptance of genetic engineering. The industry won a victory last week when a panel of the World Trade Organization ruled that the European Union had violated trade rules by halting approvals of new biotech crops. But the ruling is not expected to overcome the wariness of European consumers over these foods.
New crops are also important for the industry, which has been promoting the same two advantages - herbicide tolerance and insect resistance - for 10 years. "We haven't seen any fundamentally new traits in a while," said Michael Fernandez, executive director of the Pew Initiative on Food and Biotechnology, a nonprofit group.
Now, some new types of crops are appearing. Monsanto has just won U.S. approval for a type of genetically engineered corn promoted as having greater nutritional value - albeit only for pigs and poultry.
The corn, possessing a bacterial gene, contains increased levels of lysine, an amino acid that is often provided to farm animals as a supplement.
Coming next, industry executives say, are soybean oils intended to yield healthier baked goods and fried foods. To keep soybean oil from turning rancid, the oil typically undergoes a process called hydrogenation. The process produces trans fatty acids, which are harmful and must be disclosed in food labels under new regulations.
Both Monsanto and DuPont, which owns the Pioneer Hi-Bred seed company, have developed soybeans with altered oil composition that, in some cases, do not require hydrogenation. The cereal maker Kellogg said in December that it would use the products, particularly Monsanto's, to remove trans fats from some of its products.
Monsanto's product, Vistive, and DuPont's, which is called Nutrium, were developed by conventional breeding. They are genetically engineered only in the sense that they have the gene that allows them to grow even when sprayed with the widely used herbicide Roundup. But Monsanto and DuPont say the next generation of soybean, which would be able to eliminate trans fats in more foods, would probably require genetic engineering. Those products are expected in three to six years.
Beyond that, both companies said, would be soybeans high in omega-3 fatty acids, which are good for the heart and the brain. These are now derived largely from eating fish, which in turn get them by eating algae. Putting algae genes into soybeans could allow for soy oil that is rich in the fatty acids.
"Our hope is it is easier to formulate into food without it smelling or tasting fishy," said David Stark, vice president for consumer traits at Monsanto.
Other second-generation crops are also on the way. DuPont is trying to develop better-tasting soy for use in products like protein bars.
Stark said Monsanto had not anticipated that use of genetic engineering would discourage food companies from using the company's soybeans.
Still, opposition by consumers and food companies has clearly forced big companies like Monsanto and DuPont to choose their projects carefully. It has also made it difficult for academic scientists and small start-up companies, which typically provide much of the innovation in other fields, to obtain financing.
William Freese, a research analyst at Friends of the Earth, which opposes genetically engineered crops, said genetic engineering had been oversold. "The facts show that conventional breeding is more successful at delivering crops with 'healthy traits' than genetic manipulation, despite all the hype from Monsanto and other biotech companies," he wrote in an e-mail message.
Scientists at the International Maize and Wheat Improvement Center in Mexico have already used conventional breeding to develop corn rich in lysine, similar to the new Monsanto product, he said.
Biotechnology companies concede that if improvements can be made conventionally, results will come quicker, because such crops do not face regulatory scrutiny.
"Source":[ http://www.checkbiotech.org/root/index.cfm?fuseaction=news&doc_id=12245&start=1&control=215&page_start=1&page_nr=101&pg=1].