Blood made suitable for all

Scientists have discovered enzymes that can efficiently convert blood groups A, B and AB into the 'universal' O group — which can be given to anyone but is always in short supply. The two novel glycosidase enzymes were identified in bacteria by an international team led by Henrik Clausen of the University of Copenhagen in Denmark. The researchers hope that the enzymes will both improve the erratic supplies of blood around the world, and also the safety of transfusions. Clinical trials to test the safety and effectiveness of their converted blood are being planned. The ABO blood-type system is based on the presence or absence of the sugar-based antigens 'A' and 'B' on red blood cells. Type O blood cells have neither A nor B antigens, so may be safely transfused into anyone. But types A, B and AB blood do, and cause life-threatening immune reactions if they are given to patients with a different blood group. The bacterial glycosidase enzymes strip these antigens away from A, B and AB blood.... Whole article: "www.nature.com":[ http://www.nature.com/news/2007/070326/full/070326-17.html]

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