Compound Derived from Curry Spice Is Neuroprotective Against Stroke and Traumatic Brain Injury
Date: 12.1.2011
A synthetic derivative of the curry spice turmeric, made by scientists at the Salk Institute for Biological Studies, dramatically improves the behavioral and molecular deficits seen in animal models of ischemic stroke and traumatic brain injury (TBI). Two new studies suggest that the novel compound may have clinical promise for these conditions, which currently lack good therapies.
Study showed that CNB-001 was effective in preventing the behavioral deficits caused by stroke. The study, published in the Dec. 2, 2010 edition of the Journal of Neurochemistry, also demonstrated that the Salk compound has a direct protective effect on nerve cells within the brain.
Original Paper:
Paul A. Lapchak, David R. Schubert, Pamela A. Maher. Delayed treatment with a novel neurotrophic compound reduces behavioral deficits in rabbit ischemic stroke. Journal of Neurochemistry, 2011; 116 (1): 122 DOI: 10.1111/j.1471-4159.2010.07090.x
Source:
http://www.salk.edu/news/pressrelease_details.php?press_id=456
