Discovery of tuberculosis bacterium enzyme paves way for new TB drugs

A team of University of Maryland scientists has paved the way for the development of ****new drug therapies to combat active and asymptomatic (latent) tuberculosis infections by characterizing the unique structure and mechanism of an enzyme in **M. tuberculosis**, the bacterium that causes the disease. "The **NAD+ synthetase enzyme** that our study describes is absolutely essential for the survival of the tuberculosis bacteria and an important drug target. We can now use the information we have about its structure and mechanism to develop inhibitors for this enzyme," Gerratana explained. More "Physorg":[ http://www.physorg.com/news157386596.html]

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