Exposure to Common Environmental Bacteria May Be Source of Some Allergic Inflammation
Date: 3.2.2012
New research published in the Journal of Leukocyte Biology suggests that certain strains of Pseudomonas aeruginosa cause white blood cells to produce high levels of histamine, which worsens the severity of inflammation and infection.
To make this discovery, scientists studied the effect of two strains of pseudomonas bacteria on isolated mouse white blood cells tasked with killing bacteria, called neutrophils. Results showed that one strain killed the neutrophils, but the second strain produced substances that caused the neutrophils to increase their production of histamine significantly.
