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Eye Proteins Have Germ-Killing Power, Could Lead to New Antimicrobial Drugs

Date: 1.10.2012 

When it comes to germ-busting power, the eyes have it, according to a discovery by UC Berkeley researchers that could lead to new, inexpensive antimicrobial drugs. Proteins in the eye can help keep pathogens at bay, finds a new UC Berkeley study.

A team of UC Berkeley vision scientists has found that small fragments of keratin protein in the eye play a key role in warding off pathogens.

The findings, to be published in the October issue of the Journal of Clinical Investigation, could lead to a powerful new weapon in the battle against disease-causing invaders. These keratin fragments are relatively easy to manufacture, making them good candidates for low-cost therapeutics, the study authors said.

"What's really exciting is that the keratins in our study are already in the body, so we know that they are not toxic, and that they are biocompatible," said the study's principal investigator, Suzanne Fleiszig, a professor at UC Berkeley's School of Optometry who specializes in infectious diseases and microbiology. the potential to be designed to selectively kill specific pathogens," said Tam.

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