Human Genome-Wide Association Studies

**Genome-wide association studies** (GWAS) are a powerful method for identifying **disease** susceptibility genes for common **diseases**, offering the promise of novel targets for therapeutic intervention that act on the root cause of disease. GWAS involve scanning thousands of samples, either as case-control cohorts or in family trios, utilizing hundreds of thousands of SNP markers located throughout the **human genome**. Algorithms are applied that compare the frequencies of either single SNP **alleles**, **genotypes**, or multimarker haplotypes between disease and control cohorts. Whole article "genengnews.com":[ http://www.genengnews.com/articles/chtitem.aspx?tid=1970]

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