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Genetically engineered T cells render HIV\'s harpoon powerless

25.11.2016   |   Press monitoring

When HIV attacks a T cell, it attaches itself to the cell's surface and launches a "harpoon" to create an opening to enter and infect the cells. To stop the invasion, researchers from the Penn Center for AIDS Research at the University of Pennsylvania and scientists from Sangamo BioSciences, Inc. have developed genetically engineered T cells...

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Neovacs signs production partnership with 3P Biopharmaceuticals, a leading GMP producer of biological drugs

23.11.2016   |   Press monitoring

Paris and Boston, November 23, 2016 - Neovacs (Alternext Paris: ALNEV), a leader in active immunotherapies for the treatment of autoimmune diseases, today announced a partnership with 3P Biopharmaceuticals, a leader in the production of biological drugs, for the manufacture of interferon alpha (IFNalpha). Today's collaboration follows the recent...

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Thermal walkie-talkies instruct bacteria to deliver drugs and self-destruct

23.11.2016   |   Press monitoring

A new study from Caltech suggests a way to control bacteria, by manipulating the temperature around them to trigger when and where they release medicine, and when they might need to self-destruct. Already, microbes are being tested for their ability to fight disease, but being sent into the body without a clear goal isn't enough, as they tend to...

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Engineers make nanoscale muscles powered by DNA

21.11.2016   |   Press monitoring

The base pairs found in DNA are key to its ability to store protein-coding information, but they also give the molecule useful structural properties. Getting two complementary strands of DNA to zip up into a double helix can serve as the basis of intricate physical mechanisms that can push and pull molecular-scale devices. Engineers at the...

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Scientists are using the enzyme that makes fireflies glow to track brain cells

18.11.2016   |   Press monitoring

Fireflies and other bioluminescence-producing species (e.g. bacteria, jellyfish, worms, sharks) create light through a chemical reaction in their body catalyzed by an enzyme called luciferase. Now, a team of scientists from Vanderbilt University are using a genetically modified form of that same enzyme to make brain cells glow-in-the-dark. The...

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Chinese group injects CRISPR edited cells into human test subject for first time

16.11.2016   |   Press monitoring

A team of researchers working at West China Hospital in Chengdu has for the first time injected CRISPR–Cas9 edited cells into a human test subject. Nature reports that the procedure occurred on October 28, and that thus far, the patient is doing "fine." Modified cells have been injected into human subjects before, of course, but using different...

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Decoding the genome of the Japanese morning glory

15.11.2016   |   Press monitoring

Researchers in Japan have successfully decoded the entire Japanese morning glory genome. Japanese morning glories (Ipomoea nil) are traditional garden plants that are popular in Japan. You can see the flower in many Japanese gardens in the summer. Further, mutants are known to frequently appear in morning glories due to the actions of "jumping...

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USB-Sized Device Can Detect HIV in Under 30 Minutes

11.11.2016   |   Press monitoring

An HIV-positive diagnosis was often seen as a death sentence 20 years ago. Today, medical advancements have made it possible for positive-status patients to live long, normal lives in countries where drug therapies are available, but cost and time hurdles can make monitoring treatment cumbersome. Scientists at Imperial College London and...

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Faster diagnosis of sepsis pathogens

9.11.2016   |   Press monitoring

Microbial pathogens can be diagnosed unambiguously and within just 24 hours by means of high-throughput sequencing of their genetic makeup and special bioinformatics evaluation algorithms. Fraunhofer researchers have validated this in a clinical study with sepsis patients. It is estimated that in Germany alone around 150,000 people fall ill with...

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Gatekeeping proteins to aberrant RNA—“You shall not pass“

7.11.2016   |   Press monitoring

Mistakes happen. This is the case in the process of transporting genetic information in cells. How our cells keep errors in this process in check is the subject of a new paper by researchers at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab). They found that RNA-binding proteins are regulated such that gateway...

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