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Researchers engineer in vivo delivery system for prime editing, partially restoring vision in mice
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Researchers engineer in vivo delivery system for prime editing, partially restoring vision in mice

10.1.2024   |   Press monitoring

Prime editing, a versatile form of gene editing that can correct most known disease-causing genetic mutations, now has a new vehicle to deliver its machinery into cells in living animals. A team of researchers at the Broad Institute of MIT and Harvard has engineered virus-like particles to deliver prime editors to cells in mice at a high enough...

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In a breakthrough, diabetics damaged cells regenerated to produce insulin
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In a breakthrough, diabetics damaged cells regenerated to produce insulin

8.1.2024   |   Press monitoring

For many years, research has focused on identifying novel therapies that stimulate beta-cell growth and function to restore insulin production in type 1 diabetics. Now, in an exciting breakthrough, researchers at the Baker Heart and Diabetes Institute in Melbourne, Australia, have brought us a step closer to making this a reality, regenerating...

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Inhalable sensors could enable early lung cancer detection
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Inhalable sensors could enable early lung cancer detection

5.1.2024   |   Press monitoring

Using a new technology developed at MIT, diagnosing lung cancer could become as easy as inhaling nanoparticle sensors and then taking a urine test that reveals whether a tumor is present. The new diagnostic is based on nanosensors that can be delivered by an inhaler or a nebulizer. If the sensors encounter cancer-linked proteins in the lungs,...

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mRNA skin cancer therapy halves risk of death in clinical trial
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mRNA skin cancer therapy halves risk of death in clinical trial

3.1.2024   |   Press monitoring

Moderna has announced the results of a Phase 2b trial investigating its mRNA treatment for skin cancer, and it continues a streak of promising news. When paired with an immunotherapy, the treatment significantly reduced the risks of recurrence, metastasis and death compared to existing treatments alone, paving the way for trials against other...

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Plant non-steroidal anti-inflammatory leaves immune system intact
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Plant non-steroidal anti-inflammatory leaves immune system intact

1.1.2024   |   Press monitoring

Review and meta-analysis found that administering corticosteroids to patients with mild COVID-19 – those who did not require oxygen – was more detrimental than beneficial. Steroids given early in the disease appeared to weaken a person’s innate immunity, which develops when the body encounters a pathogen for the first time. Nonetheless,...

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Using AI, researchers identify a new class of antibiotic candidates that can kill a drug-resistant bacterium

29.12.2023   |   Press monitoring

Using a type of artificial intelligence known as deep learning, MIT researchers have discovered a class of compounds that can kill a drug-resistant bacterium that causes more than 10,000 deaths in the United States every year. In a study appearing in Nature, the researchers showed that these compounds could kill methicillin-resistant...

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Researchers develop electronic soil that enhances crop growth

27.12.2023   |   Press monitoring

Barley seedlings grow on average 50% more when their root system is stimulated electrically through a new cultivation substrate. In a study published in the journal PNAS, researchers from Linköping University have developed an electrically conductive "soil" for soilless cultivation, known as hydroponics. "The world population is increasing,...

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How jellyfish regenerate functional tentacles in days
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How jellyfish regenerate functional tentacles in days

25.12.2023   |   Press monitoring

At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days – but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing...

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Fresh research for fresh air: Harnessing microbes for removing indoor pollutants
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Fresh research for fresh air: Harnessing microbes for removing indoor pollutants

22.12.2023   |   Press monitoring

Researchers in Chile have designed an indoor air purification prototype which uses microorganisms to capture and degrade pollutants, with efficiencies above 90%. In the study, published in the Journal of Chemical Technology and Biotechnology, the scientists demonstrated that the system could operate for eight months without any loss in...

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New possibilities for the medical use of botulinun toxin A1

20.12.2023   |   Press monitoring

PSI researchers have discovered a surprising trick that could expand the possibilities for medical use of botulinun toxin A1, better known under the name Botox, as an active agent. They have developed antibody-like proteins that speed up the enzyme's effect on the transmission of nerve signals. This suggests that Botox might, for example, be able...

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