Press monitoring

The presence of clonal cell subpopulations in peripheral blood and bone marrow of patients with refractory cytopenia with multilineage dysplasia but not in patients with refractory anemia may reflect a multistep pathogenesis of myelodysplasia

3.6.2006   |   Press monitoring

Cermak J, Belickova M, Krejcova H, Michalova K, Zilovcova S, Zemanova Z, Brezinova J, Sieglova Z. Institute of Hematology and Blood Transfusion, Prague, Czech Republic. cermak@uhkt.cz A clonal origin of hematopoiesis was studied by investigation of X-chromosome inactivation patterns (XCIP) in isolated granulocyte, CD14(+) and CD3(+)...

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Changes in leptin, leptin receptor and fatty acids levels during chemoradiotherapy for oesophageal cancer

2.6.2006   |   Press monitoring

Zemanova M, Petruzelka L, Pazdrova G, Haluzik M, Novak F, Svobodnik A. Onkologicka klinika 1. LF UK a VFN, Praha. milada.zemanova@vfn.cz BACKGROUND: Oesophageal cancer patients with substantial weight loss have worse prognosis. Weight loss is often refractory to the nutritional support. Causes of the weight loss are multiple: oesophageal...

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The use of quantitative assessment of Wilms tumour gene 1 for monitoring of residual disease in acute myeloid leukemia patients

2.6.2006   |   Press monitoring

Polak J, Markova J, Schwarz J, Maaloufova J, Volkova Z, Cermak J, Haskovec C. Ustav hematologie a krevni transfuze, Praha. japol@uhkt.cz BACKGROUND: Despite a considerable effort, the majority of acute myeloid leukaemia (AML) patients do not have a suitable specific molecular marker for monitoring minimal residual disease (MRD)....

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Researchers Find Protein that Silences Genes

2.6.2006   |   Press monitoring

A team of researchers, including biologists at Washington University in St. Louis, has discovered the key role one protein plays in a major turn-off -- in this case, the turning off of thousands of nearly identical genes in a hybrid plant.

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Separation of nuclear protein complexes by blue native polyacrylamide gel electrophoresis

1.6.2006   |   Press monitoring

Novakova Z, Man P, Novak P, Hozak P, Hodny Z. Department of Cell Ultrastructure and Molecular Biology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Praque, Czech Republic. The nucleus is a highly structured organelle with distinct compartmentalization of specific functions. To understand the functions of...

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Prognostic significance of del(20q) in patients with hematological malignancies

1.6.2006   |   Press monitoring

Brezinova J, Zemanova Z, Ransdorfova S, Sindelarova L, Siskova M, Neuwirtova R, Cermak J, Michalova K. Institute of Hematology and Blood Transfusion, U Nemocnice 1, 128 20 Prague 2, Czech Republic. brez@uhkt.cz Deletions of the long arm of chromosome 20 represent a common chromosomal abnormality associated with myeloid malignancies, in...

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Enzyme Inhibitor May Help Lower Cholesterol And Unclog Arteries

1.6.2006   |   Press monitoring

Atherosclerosis, the accumulation of cholesterol in the arteries that clogs the circulation and results in heart attacks and strokes, is a leading cause of death. One strategy for preventing heart disease and stroke is to clear out clogged arteries, restoring circulation. This process, known as reverse cholesterol transport is accomplished by the...

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Is the European Union ready for the biotechnology challenge? A round table in Portoroz, Slovenia

31.5.2006   |   Press monitoring

Portoroz, Slovenia, May the 29th. In 1990, Europe was stronger in biotechology R&D than the USA, but today it is lagging behind. Since biotechnology is going to be one of the key industries of the 21th century, Europe should move quickly, as newcommers like India are moving in. This is the message of the round table on the future of biotechnology...

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Visualization of nodulation gene activity on the early stages of Rhizobium leguminosarum bv. viciae symbiosis

31.5.2006   |   Press monitoring

Chovanec P, Novak K. Institute of Microbiology, Academy of Sciences of the Czech Republic, 142 20 Prague, Czechia. A technique was optimized for the in situ detection of nodulation (nod) gene activity in Rhizobium leguminosarum bv. viciae symbiosis with compatible plant hosts Vicia tetrasperma (L.) SCHREB. and Pisum sativum...

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