Press monitoring

The Future of Regulatory Toxicology: Impact of the Biotechnology Revolution

5.4.2006   |   Press monitoring

The molecular biology revolution and the advent of genomic and proteomic technologies are facilitating rapid advances in our understanding of the molecular details of cell and tissue function.

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Allergen-responsive CD4+CD25+ Regulatory T Cells in Children who Have Outgrown Cow's Milk Allergy

5.4.2006   |   Press monitoring

Cow's milk allergy in children is often of short duration, which makes this disorder an interesting clinical model for studies of tolerance to dietary antigens.

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Proteins sail away with new NMR approach

5.4.2006   |   Press monitoring

Using NMR to determine protein structure has two enormous advantages over traditional crystallographic methods.

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Pharmacological promotion of inclusion formation: A therapeutic approach for Huntington’s and Parkinson’s diseases

5.4.2006   |   Press monitoring

Misfolded proteins accumulate in many neurodegenerative diseases, including huntingtin in Huntington’s disease and -synuclein in Parkinson’s disease.

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Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2

5.4.2006   |   Press monitoring

Akt1 is frequently up-regulated in human tumors and has been shown to accelerate cell proliferation and to suppress programmed cell death; consequently, inhibition of the activity of Akt1 has been seen as an attractive target for therapeutic intervention.

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Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation

5.4.2006   |   Press monitoring

Ribonucleotide reductase catalyzes a crucial step in de novo DNA synthesis and is allosterically controlled by relative levels of dNTPs to maintain a balanced pool of deoxynucleoside triphosphates in the cell. In eukaryotes, the enzyme comprises a heterooligomer of 2 and 2 subunits.

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Study Shows Nanoparticles Could Damage Plant Life

5.4.2006   |   Press monitoring

A nanoparticle commonly used in industry could have a damaging effect on plant life, according to a report by an environmental scientist at New Jersey Institute of Technology (NJIT).

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Scientists measure nanoparticle safety

5.4.2006   |   Press monitoring

Researchers at the University of California, Los Angeles (UCLA), US, have used tests developed for air pollution to predict the safety of nanomaterials. The tests indicate the ability of nanoparticles to generate toxic oxygen radicals that can cause tissue injury such as inflammation.

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Genetic network guards against DNA damage

5.4.2006   |   Press monitoring

CHICAGO -- University of Illinois scientists say they've developed an innovative strategy of mixing lipids and nanoparticles to produce new drug delivery vehicles.

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