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Scientists turn toxic pesticide into treatment against antibiotic-resistant bacteria

4.1.2021   |   Press monitoring

N-Aryl-C-nitroazoles are an important class of heterocyclic compounds. They are used as pesticides and fungicides. However, these substances could be toxic to humans and cause mutations. As they are not frequently used, there is little data about them in the medicinal chemistry literature. However, it has been suggested recently that the groups...

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Weedy Seadragon genomics reveal highly distinct populations
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Weedy Seadragon genomics reveal highly distinct populations

1.1.2021   |   Press monitoring

Charismatic, iconic and Instagram-friendly, the weedy seadragon is a favorite with divers and snorkellers. The first genomic study of east coast Australian seadragon populations can now reveal "weedies" from NSW, Victoria and Tasmania are significantly different. The study, published in PLOS ONE, also reveals that Victorian weedy seadragons may...

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Reston ebolavirus spreads efficiently in pigs
Credit: Cynthia Goldsmith_Wikipedia

Reston ebolavirus spreads efficiently in pigs

30.12.2020   |   Press monitoring

Reston ebolavirus (RESTV) should be considered a livestock pathogen with potential to affect other mammals, including people, according to National Institutes of Health scientists. Scientists found that experimental piglets infected with RESTV developed severe respiratory disease and shed the virus from the upper respiratory tract. RESTV can...

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New gene family of antimicrobial proteins discovered in German cockroaches
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New gene family of antimicrobial proteins discovered in German cockroaches

28.12.2020   |   Press monitoring

Researchers from The Institute for Integrative Systems Biology have discovered a new gene family of antimicrobial peptides (small proteins) – the Blattellicins – in a German cockroach (Blattella germanica). The study, published in the journal Scientific Reports, may help to understand how these insects can live in unsanitary environments and...

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Genetic engineering without unwanted side effects helps fight parasites
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Genetic engineering without unwanted side effects helps fight parasites

25.12.2020   |   Press monitoring

Modified CRISPR-Cas9 gene editing scissors are enabling researchers at the University of Zurich to make alterations to the genetic material of single-cell organisms that are indistinguishable from natural mutations. This method makes it possible to develop a harmless experimental live vaccine for the widespread parasite Toxoplasma gondii. Around...

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Eight Proteins Turn Mouse Stem Cells into Egglike Cells
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Eight Proteins Turn Mouse Stem Cells into Egglike Cells

23.12.2020   |   Press monitoring

The identification of the transcription factors that elicit oocyte growth will aid reproductive biology research and might help women with fertility issues, scientists say. A core set of eight proteins can transform stem cells from mice into cells that look a lot like immature egg cells called oocytes. The egglike cells could not undergo meiosis...

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Scientists create a new phototoxic protein, SuperNova2

21.12.2020   |   Press monitoring

Scientists from Skoltech, the Institute of Bioorganic Chemistry of RAS and the London Institute of Medical Sciences (LMS) have developed an enhanced version of SuperNova, a genetically encoded phototoxic synthesizer, that helps control intracellular processes by light exposure. An important research tool, phototoxic proteins are used as...

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Researchers develop novel nanoparticle that efficiently and selectively kills cancer cells
Credit: CONTIPRO

Researchers develop novel nanoparticle that efficiently and selectively kills cancer cells

18.12.2020   |   Press monitoring

Many chemotherapeutic agents used to treat cancers are associated with side-effects of varying severity, because they are toxic to normal cells as well as malignant tumors. This has motivated the search for effective alternatives to the synthetic pharmaceuticals with which most cancers are currently treated. The use of calcium phosphate and...

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Synthetic molecules mimic human cells to lure and kill the flu virus

16.12.2020   |   Press monitoring

The influenza virus as proven to be a very tricky foe to fight. Now, researchers at EPFL in Switzerland have developed synthetic molecules that can kill the flu virus by mimicking human cells, and putting the squeeze on the virus when it attaches itself to the decoy. Current antiviral drugs, such as oseltamivir (or Tamiflu), work by attacking the...

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Immunity-boosting silica nanoparticles could replace pesticides

14.12.2020   |   Press monitoring

Pesticides may indeed kill plant pathogens, but they're also harmful to the environment. Newly developed nanoparticles may provide a more eco-friendly alternative, as they boost the immune systems of crop plants, then harmlessly dissolve. Occurring naturally in soil, a compound known as silicic acid has for some time been known to provoke...

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