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An mRNA vaccine for cancer immunotherapy
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An mRNA vaccine for cancer immunotherapy

24.2.2021   |   Press monitoring

Messenger RNA (mRNA) vaccines to prevent COVID-19 have made headlines around the world recently, but scientists have also been working on mRNA vaccines to treat or prevent other diseases, including some forms of cancer. Now, researchers reporting in ACS' Nano Letters have developed a hydrogel that, when injected into mice with melanoma, slowly...

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Treating rheumatoid arthritis with micromotors

22.2.2021   |   Press monitoring

Rheumatoid arthritis is a chronic inflammatory disorder marked by joint pain, swelling and damage. Although medications, such as steroids, anti-inflammatory drugs and immunosuppressants, can help slow joint destruction and relieve pain, they have side effects and aren't completely successful. Now, researchers reporting in ACS' Nano Letters have...

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Researchers unveil detailed genome of invasive malaria mosquito
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Researchers unveil detailed genome of invasive malaria mosquito

19.2.2021   |   Press monitoring

Despite the broad notoriety of sharks, snakes, scorpions and other formidable creatures, mosquitoes remain the deadliest animal on the planet… by far. Mosquito-transmitted malaria remains the number one worldwide killer among vector-borne diseases, claiming more than 400,000 human lives in 2019. In order to engineer advanced forms of defense...

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Photosynthetic bacteria-based cancer optotheranostics

17.2.2021   |   Press monitoring

Cancer is one of the most thought-provoking healthcare problems throughout the world. The development of therapeutic agents with highly selective anti-cancer activities is increasingly attractive due to the lack of tumor selectivity of conventional treatments. Scientists at Japan Advanced Institute of Science and Technology (JAIST) have created a...

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Scientists identify how harmless gut bacteria turn bad

15.2.2021   |   Press monitoring

An international team of scientists has determined how harmless E. coli gut bacteria in chickens can easily pick up the genes required to evolve to cause a life-threatening infection. Their study, published in Nature Communications, warns that such infections not only affect the poultry industry but could also potentially cross over to infect...

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Machine-learning how to create better AAV gene delivery vehicles

12.2.2021   |   Press monitoring

Adeno-associated viruses (AAVs) have become promising vehicles for delivering gene therapies to defective tissues in the human body because they are non-pathogenic and can transfer therapeutic DNA into target cells. However, while the first gene therapy products approved by the Federal Drug Administration (FDA) use AAV vectors and others are...

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Plant-based magnetic nanoparticles with antifungal properties

10.2.2021   |   Press monitoring

A team of researchers from Immanuel Kant Baltic Federal University obtained magnetic nanoparticles using sweet flag (Acorus calamus). Both the roots and the leaves of this plant have antioxidant, antimicrobial, and insecticide properties. The extract of sweet flag was used as a non-toxic reagent for the manufacture of coated particles. The...

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Machine learning generates realistic genomes for imaginary humans

8.2.2021   |   Press monitoring

Machines, thanks to novel algorithms and advances in computer technology, can now learn complex models and even generate high-quality synthetic data such as photo-realistic images or even resumes of imaginary humans. A study recently published in the international journal PLOS Genetics uses machine learning to mine existing biobanks and generate...

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Researchers engineer a tiny antibody capable of neutralizing the coronavirus
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Researchers engineer a tiny antibody capable of neutralizing the coronavirus

5.2.2021   |   Press monitoring

Michael Schoof, a graduate student in the lab of Peter Walter, Ph.D., a renowned scientist specializing in protein sorting and cellular membranes, was part of a small team on a quixotic mission: to immobilize SARS-CoV-2, the novel coronavirus that causes COVID, by using a synthetic version of tiny antibodies originally discovered in llamas and...

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Breast cancer-on-a-chip for testing immunotherapy drugs
Credit: psdesign1 - Fotolia.com

Breast cancer-on-a-chip for testing immunotherapy drugs

3.2.2021   |   Press monitoring

In recent years, scientists have been trying to develop "checkpoint inhibitor" drugs which will counteract these suppressive checkpoint interactions in order to re-activate the body's immune response to tumor cells. One of these drugs is U.S. FDA approved to treat metastatic melanoma; others are available or under development to treat other...

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