Press monitoring
Artificial enzyme could slow Parkinsons by targeting protein clumps
8.1.2021 | Press monitoring
Neurodegenerative diseases like Parkinson’s are characterized by clumps of misfolded proteins accumulating and killing brain cells. Now, researchers at Johns Hopkins have developed an artificial enzyme that may stop these clumps from spreading, providing a new potential treatment for Parkinson’s. Alpha-synuclein is an abundant protein in the...
Supercomputers simulate new pathways for potential RNA virus treatment
6.1.2021 | Press monitoring
University of New Hampshire (UNH) researchers recently used Comet at the San Diego Supercomputer Center at UC San Diego and Stampede2 at the Texas Advanced Computing Center to identify new inhibitor binding/unbinding pathways in an RNA-based virus. The findings could be beneficial in understanding how these inhibitors react and potentially help...
Scientists turn toxic pesticide into treatment against antibiotic-resistant bacteria
4.1.2021 | Press monitoring
N-Aryl-C-nitroazoles are an important class of heterocyclic compounds. They are used as pesticides and fungicides. However, these substances could be toxic to humans and cause mutations. As they are not frequently used, there is little data about them in the medicinal chemistry literature. However, it has been suggested recently that the groups...
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Weedy Seadragon genomics reveal highly distinct populations
1.1.2021 | Press monitoring
Charismatic, iconic and Instagram-friendly, the weedy seadragon is a favorite with divers and snorkellers. The first genomic study of east coast Australian seadragon populations can now reveal "weedies" from NSW, Victoria and Tasmania are significantly different. The study, published in PLOS ONE, also reveals that Victorian weedy seadragons may...
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Reston ebolavirus spreads efficiently in pigs
30.12.2020 | Press monitoring
Reston ebolavirus (RESTV) should be considered a livestock pathogen with potential to affect other mammals, including people, according to National Institutes of Health scientists. Scientists found that experimental piglets infected with RESTV developed severe respiratory disease and shed the virus from the upper respiratory tract. RESTV can...
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New gene family of antimicrobial proteins discovered in German cockroaches
28.12.2020 | Press monitoring
Researchers from The Institute for Integrative Systems Biology have discovered a new gene family of antimicrobial peptides (small proteins) – the Blattellicins – in a German cockroach (Blattella germanica). The study, published in the journal Scientific Reports, may help to understand how these insects can live in unsanitary environments and...
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Genetic engineering without unwanted side effects helps fight parasites
25.12.2020 | Press monitoring
Modified CRISPR-Cas9 gene editing scissors are enabling researchers at the University of Zurich to make alterations to the genetic material of single-cell organisms that are indistinguishable from natural mutations. This method makes it possible to develop a harmless experimental live vaccine for the widespread parasite Toxoplasma gondii. Around...
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Eight Proteins Turn Mouse Stem Cells into Egglike Cells
23.12.2020 | Press monitoring
The identification of the transcription factors that elicit oocyte growth will aid reproductive biology research and might help women with fertility issues, scientists say. A core set of eight proteins can transform stem cells from mice into cells that look a lot like immature egg cells called oocytes. The egglike cells could not undergo meiosis...
Scientists create a new phototoxic protein, SuperNova2
21.12.2020 | Press monitoring
Scientists from Skoltech, the Institute of Bioorganic Chemistry of RAS and the London Institute of Medical Sciences (LMS) have developed an enhanced version of SuperNova, a genetically encoded phototoxic synthesizer, that helps control intracellular processes by light exposure. An important research tool, phototoxic proteins are used as...
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Researchers develop novel nanoparticle that efficiently and selectively kills cancer cells
18.12.2020 | Press monitoring
Many chemotherapeutic agents used to treat cancers are associated with side-effects of varying severity, because they are toxic to normal cells as well as malignant tumors. This has motivated the search for effective alternatives to the synthetic pharmaceuticals with which most cancers are currently treated. The use of calcium phosphate and...
