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Stem cells from baby teeth patch up dental injuries in clinical trial

14.9.2018   |   Press monitoring

Your teeth are one of the only parts of your body that can't naturally repair themselves – so when a kid injures a permanent tooth at a young age, they're stuck with that for life. But a new clinical trial has shown promising results in using dental stem cells derived from a patient's baby teeth to bring a "dead" tooth back to life. The...

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Unleashing TIGER on small RNAs

12.9.2018   |   Press monitoring

Efforts to explore the landscape of small RNAs (sRNAs) – short RNA molecules that are poorly understood – often use high-throughput sequencing (sRNA-seq). These efforts are hampered by a lack of tools to identify, quantify and analyze all the different sRNAs in sRNA-seq datasets. Kasey Vickers, PhD, and colleagues have now developed a new...

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Superbugs jumping frequently between humans and animals

10.9.2018   |   Press monitoring

MRSA staphylococcus is an example of a superbug. These bacterial strains are resistant to most antibiotics and can cause serious infections. "In the case of MRSA, these bacteria have also spread in hospitals almost worldwide," says Jukka Corander, professor at the University of Helsinki, a member of an international research team that mapped...

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Neutrophil nanosponges soak up proteins that promote rheumatoid arthritis

7.9.2018   |   Press monitoring

Engineers at the University of California San Diego have developed neutrophil "nanosponges" that can safely absorb and neutralize a variety of proteins that play a role in the progression of rheumatoid arthritis. Injections of these nanosponges effectively treated severe rheumatoid arthritis in two mouse models. Administering the nanosponges...

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Scientists decode opium poppy genome

5.9.2018   |   Press monitoring

Scientists have determined the DNA code of the opium poppy genome, uncovering key steps in how the plant evolved to produce the pharmaceutical compounds used to make vital medicines. The discovery may pave the way for scientists to improve yields and the disease resistance of the medicinal plant, securing a reliable and cheap supply of the most...

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Can a transgenic chestnut restore a forest icon?

3.9.2018   |   Press monitoring

American chestnuts, towering 30 meters or more, once dominated forests throughout the Appalachian Mountains. But in the early 1900s, a fungal infection appeared on trees at the Bronx Zoo in New York City, and then spread rapidly. The so-called chestnut blight – an accidental import from Asia – releases a toxin that girdles trees and kills...

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Prototype bionic eye created with custom 3D printer

31.8.2018   |   Press monitoring

When he was an assistant professor at Princeton University, Michael McAlpine led the development of a 3D-printed bionic ear. Now an associate professor at the University of Minnesota, he has gone on to 3D-print a rudimentary bionic eye – and it could eventually lead to versions capable of replacing the real thing. A McAlpine-led team began with a...

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Metabolic engineering of E. coli for the secretory production of free haem

29.8.2018   |   Press monitoring

Researchers of KAIST have defined a novel strategy for the secretory production of free haem using engineered Escherichia coli (E. coli) strains. They utilized the C5 pathway, the optimized downstream pathways, and the haem exporter to construct a recombinant micro-organism producing extracellular haem using fed-batch fermentation. This is the...

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Enzymes produced by gut bacteria can make universal blood more efficiently

27.8.2018   |   Press monitoring

For several decades researchers have been working to find an effective way to convert one blood type into another. Type O blood, often considered the universal blood type, is most useful in emergency situations. New research presented at the National Meeting & Exposition of the American Chemical Society has revealed that an enzyme produced by gut...

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Newly discovered class of molecules may boost cancer vaccine development

24.8.2018   |   Press monitoring

Cancer vaccines are designed to heighten the immune system's awareness of a tumor's unique features, boosting its ability to recognize, attack, and destroy the cancer. To date, effective cancer vaccines have focused on what are called "neoantigens," tumor-specific peptides that result from acquired mutations. But not every tumor produces...

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