Publishing: BioMed Central

Journal of Translational Medicine is an Open Access, peer-reviewed online journal focussing on information derived from human experimentation so as to optimise the communication between basic and clinical science. Journal of Translational Medicine aims to improve the communication between basic and clinical science so that more therapeutic insights may be derived from new scientific ideas - and vice versa. Translation research goes from bench to bedside, where theories emerging from preclinical experimentation are tested on disease-affected human subjects, and from bedside to bench, where information obtained from preliminary human experimentation can be used to refine our understanding of the biological principles underpinning the heterogeneity of human disease and polymorphism(s). The former direction has received much attention, usually through exploratory clinical studies referred to as \"phase 1\" trials. The latter, however, has been largely ignored. The outcomes of clinical trials are usually poor and experimenters are encouraged not to publish, believing that journals are less likely to publish \"negative\" results. Consequently most of this \"transitional information\" remains hidden from the wider research community.

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