Like submicroscopic spacecrafts: Graphene flakes to control neuron aktivity

Like in a science fiction novel, miniscule spacecrafts able to reach a specific site of the brain and influence the operation of specific types of neurons or drug delivery: Graphene flakes, the subject matter of the new study of the group of SISSA professor Laura Ballerini, open up truly futuristic horizons.

Measuring just one millionth of a metre, these particles have proven able to interfere with the transmission of the signal at excitatory neuronal synaptic junctions. Furthermore, the study has shown that they do so in a reversible manner, because they disappear without leaving a trace few days after they have been administered.

Basic research could initiate further studies, geared to investigating the possible therapeutic effects for the treatment of problems, such as epilepsy, in which an excess of the activity of the excitatory neurons is recorded, or to study innovative ways to transport therapeutic substances in situ.

The research, carried out in association with the universities of Trieste, Manchester and Strasbourg, is conducted within the Graphene Flagship, the substantial funding project of the European Union, which aims to investigate the potential of graphene in the most diverse areas of applications, from the biomedicine to industry.