Career - Offer
Postdoctoral Fellowship in Organic Synthesis and Medicinal Chemistry
Type of job: full-time
Desired start date: January 2015
Form of employment: fixed-term contract for 18 months - temporary
Job description: Postdoctoral Researcher
We seek a highly motivated individual to join an EU-funded research project within laboratories of Organic Synthesis and Medicinal Chemistry that involves: synthesis of natural product-inspired, structurally complex molecules with targeted biological activity; formulation and development of essential chemical methodology; rational design and identification of novel enzyme activators/inhibitors affecting key cell-signalling pathways.
Closely interacting Laboratory of Medicinal Chemistry, headed by Dr. Kamil Paruch, and Laboratory of Organic Synthesis, headed by Dr. Jakub Švenda, host a dynamic and productive research groups at Masaryk University and provide a highly interactive research environment with state-of-the-art facilities. The Laboratory of Medicinal Chemistry is part of a unique interdisciplinary research platform - Center of Biomolecular and Cellular Engineering (CBCE), which represents one of the research platforms of International Clinical Research Centre (ICRC). ICRC is a joint research centre of St. Anne´s University Hospital in Brno and Mayo Clinic in Rochester, Minnesota (USA) and links together pre-clinical basic research (e.g. in stem cell biology, cancer biology etc.) with clinical research (for more info see http://www.fnusa-icrc.org/en/). The CBCE platform focuses on research of biologically active small molecules and engineered proteins, which currently represent the most promising tools for influencing biological processes such as genomic cell stability, cell growth, cell differentiation, cell reprogramming to pluripotency, cell death, and cell survival.
Prerequisites for successful role performance:
- Ph.D. in organic chemistry with solid prior experience in organic synthesis
- additional experience in medicinal chemistry advantageous
- history of excellent research productivity
- ability to design and execute synthesis of organic compounds of medium-to-high complexity
Professional requirements:
The applicant should have a solid expertise in organic synthesis of complex molecules. An insight into cancer biology and/or biology of stem cells would represent strong benefit. The specific requirements on the applicant are as follows:
- Hands-on experience with modern organic synthesis and characterization of stereochemically complex organic molecules (1D and 2D NMR)
- Good level of communication in English language (verbal and written)
- Presentation of results to an international audience
- Computer ability (MS Office, SciFinder, Reaxys)
Personal characteristics:
Successful candidates should be highly motivated and have independent thinking, strong organizational and communication skills and be prepared to work in a highly competitive environment.
The candidates should e-mail their Curriculum Vitae and Letter of Motivation to ales.pacner@fnusa.cz by July 30, 2014 at the latest. Applications will be processed in two steps. The first step will focus on the excellence of candidates. Those shortlisted will be invited to send two letters of recommendation and subsequently will be interviewed.
E-mail:
ales.pacner@fnusa.cz
Updated: 27.5.2014
