Career - Offer
Postdoctoral Fellowship in signalling, metastasis & microenvironment
Type of job: full-time
Desired start date: 1st February 2014
Form of employment: Full-time job, fixed-term contract for 30 months- temporary
Job description: We seek a highly motivated individual to join an EU-funded research project within Cellular Signalling Laboratory that involves: study of pathological plasticity of epithelial cells, cancer stem cell biology and study of control and regulation of signalling in cancer with an initial focus on role of autocrine/paracrine produced growth factors in invasion and metastasis.
Cellular Signalling Laboratory, headed by Dr. Karel Souček, is located at Department of Cytokinetics, Institute of Biophysics AS CR and provides a dynamic research environment with state-of-the-art facilities. Cellular Signalling Laboratory is a part of a unique interdisciplinary research platform - Center of Biomolecular and Cellular Engineering (CBCE), which represents one of the research platforms of International Clinical Research Centre (ICRC). ICRC is a joint research centre of St. Anne´s University Hospital in Brno and Mayo Clinic in Rochester, Minnesota (USA) and links together pre-clinical basic research (e.g. in stem cell biology, cancer biology etc.) with clinical research (for more info see http://www.fnusa-icrc.org/en/). The CBCE platform focuses on research of biologically active small molecules and engineered proteins, which currently represent the most promising tools for influencing biological processes such as genomic cell stability, cell growth, cell differentiation, cell reprogramming to pluripotency, cell death, and cell survival.
Prerequisites for successful role performance:
- Ph.D. in cancer biology, biomedicine with solid prior experience in molecular biology, biochemistry and cell biology; experience in animal physiology and immunology;
- First author publications in peer-reviewed English language journals
Professional requirements:
The applicant should have a solid knowledge of cell biology and cancer diseases with special focus on solid tumours. An insight into in vivo models is necessary. The experience of the applicant with basic methods of cell biology and other advanced techniques should cover the following:
- Imaging techniques e.g. fluorescence and confocal microscopy, in vivo imaging
- Small animals experimental techniques
- In vitro cell cultures including primary cell isolation and cultivation, cell transfection, migration and invasion analysis, basics in flow cytometry and sorting
- Basic molecular biochemical methodologies (western blot, qRT-PCR)
- Good level of communication in English language (verbal and written)
- Presentation of results to an international audience
- Computers (MS Office, EndNote, Statistica, Indesign, Photoshop, Adobe Acrobat)
Personal characteristics:
Successful candidates should be highly motivated and have independent thinking, strong organizational and communication skills.
Please email your application in electronic form, as a cover letter accompanied by a resume indicating details of your existing professional experience, to: karel.soucek@fnusa.cz by 15th December 2013 at the latest. Applications will be considered in two stages. The first stage will focus on the excellence of candidates. Those shortlisted will be invited to send two letters of recommendation and subsequently will be interviewed.
By responding to this invitation and/or sending your CV and any other personal materials to St. Anne's University Hospital, you consent to the collection, processing and storage of your personal data in accordance with Act No. 101/2000 Coll., the protection of personal data. You are providing St. Anne's University Hospital with these data solely for the purpose of mediating employment, the period however being no longer than one year from submitting. Should you not reclaim the materials submitted by you, they will be discarded after the period has expired.
Contact:
Dr. Karel Souček
E-mail:
karel.soucek@fnusa.cz
Updated: 25.11.2013
