Production of 5-Aminovaleric and Glutaric Acid by Metabolically Engineered Microorganism
Date: 3.1.2013
We use many different types of chemicals and plastics for the convenience of our everyday life. The current sources of these materials are provided from petrochemical industry, using fossil oil as a raw material. Due to our increased concerns on the environmental problems and fossil resource availability, there has been much interest in producing those chemicals and materials from renewable non-food biomass through biorefineries.
In the paper published in Metabolic Engineering, a Korean research team applied systems metabolic engineering approach to develop recombinant Escherichia coli for the production of 5-aminovaleric acid and glutaric acid, the promising C5 platform chemicals, by fermentation.
This study showcases the first microbial process for the production of 5AVA and glutatic acid as C5 platform chemicals by developing microbial strain through systems metabolic engineering.
