Restoring Function Of A Mutant Gene Without Altering DNA Might Be Possible
Date: 13.2.2009
Researchers at Fox Chase Cancer Center have demonstrated that it might be possible to **treat genetic diseases**, including some forms of **cancer**, by "rescuing" the misshapen, useless proteins produced by some mutant genes.
In the current issue of the Journal of Biological Chemistry, available online now, researchers detail how they were able to restore the function of a mutant human gene in a yeast model of disease by manipulating the available amounts of a so-called chaperone protein, named Hsp70, which helps amino acid chains fold into their proper protein form.
Source "Sciencedaily":[ http://www.sciencedaily.com/releases/2009/02/090211161946.htm]
