Scientists Create Computational Technique for Finding Disease-Associated Genetic Regions

Researchers developed a novel computation method that they say is designed to better identify genomic regions harboring **disease-susceptibility genes**. The approach uses **mapping by admixture linkage disequilibrium** (MALD). It looks for patterns of variation that are over-represented in groups with increased susceptibility to a particular disorder. In the current study, scientists developed a new technique for MALD called expected mutual information. “Our novel approach extends previous methods by incorporating knowledge on population admixture, drawing a more precise picture of the mosaic of ancestries along an individual's genome,” explains primary author, Sivan Bercovici from Technion-Israel Institute of Technology. Whole article on "genengnews":[ http://www.genengnews.com/news/bnitem.aspx?name=32390256&source=genwire]

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