Scientists seek key to converting algae to biofuel

University of Florida Institute of Food and Agricultural Sciences researchers may have found a key to converting algae to fuel. The scientists have found what researchers call a "transcription factor," called ROC40.

Bala Rathinasabapathi, a UF/IFAS professor of horticultural sciences, likened a transcription factor's role in controlling the expression of many genes inside the algae cells to a policeman controlling a large crowd.

To draw lipids out of algae, scientists must starve the algae of nitrogen. Among the hundreds of proteins modulated by nitrogen starvation, the synthesis of ROC40 was the most induced when the cells made the most oil. The high induction of that protein suggested to scientists that it could be playing an important biological role, said Elton Gonçalves, a former UF/IFAS doctoral student. In fact, the team's research showed that ROC40 helps control lipid production when the algal cells were starved of nitrogen.

"Our discovery about the ROC40 protein suggests that it may be increasing the expression of genes involved in the synthesis of oil in microalgae," Rathinasabapathi said.

"Such information is of great importance for the development of superior strains of algae for biofuel production," Gonçalves said. "We conducted this research due to the great socioeconomic importance of developing renewable sources of fuels as alternatives for petroleum-based fuels for future generations. In order to advance the production of algal biofuels into a large-scale, competitive scenario, it is fundamental that the biological processes in these organisms are well understood."