The insulinoma-associated 1: a novel promoter for targeted cancer gene therapy for small-cell lung cancer
Date: 27.4.2006
The insulinoma-associated 1 (INSM1) gene is expressed exclusively during early embryonal development, but has been found re-expressed at high levels in neuroendocrine tumors. The regulatory region of the INSM1 gene is therefore a potential candidate for regulating expression of a therapeutic gene in transcriptionally targeted cancer gene therapy against neuroendocrine tumors.
"Source":[
http://www.nature.com/cgt/journal/v13/n4/abs/7700887a.html].
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