*WANTED* Diploma student

If you are looking for an interesting work in a young and dynamic lab, if you want to learn a lot and make a difference, come and join us in Laboratory of Structural Biology at the Institute of Biotechnology, Academy of Sciences.

We are looking for a highly motivated student for “Structure-function studies of histone deacetylases” project. The aim of the project will be expression and characterization of histone deacetylases (HDACs). HDACs play crucial role in many physiological processes including epigenetics, protein degradation, cell motility, and receptor signaling. The work will contribute to understanding the function of these proteins in vitro as well as in the physiological context.

The diploma student will learn variety of techniques including cloning, mutagenesis, heterologous protein expression in various systems (E.coli, K.lactis, insect and mammalian cells), protein purification and characterization, enzymology, inhibition studies, and X-ray crystallography.

If interested, please contact Dr. Cyril Bařinka (cyril.barinka@img.cas.cz; phone +420 296 443 615) for more information.