Yeast could deliver insulin as a spray
Date: 2.3.2006
UK scientists think that diabetes patients could be able to receive insulin via a nasal spray using yeast, which would open up the way for a spray to be developed to replace injections.
The discovery is good news for patients that dislike the rigmarole of injections that form the basis of diabetes control and therapy. While non-injectable insulin has been hailed as the future, there are still manufacturing issues that prevent this method of drug delivery from becoming the preferred one.
Researchers from Leeds University have found that the fungus, which is normally used to make beer and bread, opened a person's nasal cells to allow insulin to pass through nose tissue. Subsequent results showed that yeast cells successfully enhanced the penetration of insulin. Preliminary research found that the yeast, which is non-toxic, opened up the tight junctions between nasal cells.
"Source":[ http://www.in-pharmatechnologist.com/news/ng.asp?n=65800-diabetes-non-injectable-insulin].
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