vasopressin

Vasopressin, also known as antidiuretic hormone (ADH), is a neurohypophysial hormone found in most mammals.

Vasopressin is responsible for regulating the body retention of water by acting to increase water absorption in the collecting ducts of the kidney nephron. Vasopressin increases water permeability of the kidney collecting duct and distal convoluted tubule by inducing translocation of aquaporin-CD water channels in the kidney nephron collecting duct plasma membrane.

Vasopressin is a peptide hormone that controls the reabsorption of molecules in the tubules of the kidneys by affecting the tissue permeability. It also increases peripheral vascular resistance, which in turn increases arterial blood pressure. It plays a key role in homeostasis, by the regulation of water, glucose, and salts in the blood. It is derived from a preprohormone precursor that is synthesized in the hypothalamus and stored in vesicles at the posterior pituitary. Most of it is stored in the posterior pituitary to be released into the bloodstream.