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coenzyme A
Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle.
All sequenced genomes encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it (or a thioester, such as acetyl-CoA) as a substrate.
It is adapted from cysteamine, pantothenate, and adenosine triphosphate.
The structure of a coenzyme A.
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